Creamy chicken breasts, spinach, garlic, and melty mozzarella come together in this comforting chicken casserole with spinach.

Remember it later!

Planning to try this recipe soon? Pin it for a quick find later!

Remember it later!

Planning to try this recipe soon? Pin it for a quick find later!

This chicken casserole with spinach didn’t start with a craving—it started with chaos. I was juggling a million things, the fridge was looking sad, and I had two chicken breasts, a block of cream cheese, and spinach that was practically begging not to be thrown out. I threw them in a casserole dish, crossed my fingers, and hoped for the best.

You know when something just works—even when you totally wing it? That was this. It’s not fancy, it’s not fussy, but oh man, it’s good. And over the years, it’s become a bit of a comfort blanket for me. There’s something kind of grounding about pulling this creamy, garlicky chicken out of the oven after a long day.

Here’s a quick peek at what’s inside:

Why You’ll Love This Chicken Casserole with Spinach Recipe?

Look, I love a good ambitious dinner… sometimes. But most nights? I just want something that tastes like effort without actually requiring much. That’s what this recipe gives you.

You’ve got juicy baked chicken, a garlic-forward cream cheese spread (yes, please), sautéed spinach for a little health flex, and melted mozzarella on top like a big, cheesy exclamation mark. No weird ingredients. No “wait, I need to marinate this for 24 hours?” nonsense.

Plus, it reheats like a dream. If there are leftovers (big if), they’re even better the next day.

Ingredient Notes:

I’m not here to tell you there’s only one way to make a chicken casserole with spinach. That’s the magic of it—it adapts to real life. Here’s what I used, and why I think it works:

Chicken breasts – I slice ‘em in half lengthwise. It’s faster, they cook more evenly, and it kind of feels like you’re getting more for your money.
Garlic – Fresh is great, but I’ve definitely used the jarred kind when I’m in a rush. No shame.
Olive oil – Just enough to carry flavor and keep things from sticking.
Red chili flakes – A tiny bit of heat to cut the richness. It’s not spicy-spicy, promise.
Italian seasoning – Honestly? It’s just whatever blend I’ve got from the store. Don’t overthink it.
Cream cheese – Go full-fat if you can. That velvety texture is worth it.
Spinach – Fresh is fab. Frozen works too, just squeeze out the water or it gets a little swampy.
Mozzarella – Melty, stretchy, a little browned on top? Chef’s kiss.

How To Make Chicken Casserole with Spinach?

So let’s walk through this thing. You don’t need to be a pro. You just need a casserole dish, a bit of trust, and maybe a glass of wine while it bakes. (Highly recommended.)

Step 1: Preheat that oven.
Crank it up to 400°F so it’s ready when you are. Nothing worse than forgetting to preheat, right?

Step 2: Toss your chicken in a bag with flavor.
Slice the breasts lengthwise so you’ve got four thinner pieces. Drop them in a zip-top bag with olive oil, garlic, chili flakes, and Italian seasoning. Give it a shake like you mean it. Let it sit while you get the other bits ready—ten, fifteen minutes is enough.

Step 3: Lay it out.
Grab your casserole dish. Arrange the chicken inside. Don’t worry if it’s not Instagram-perfect. We’re going for delicious, not staged.

Step 4: Slather on cream cheese.
This part’s messy, and that’s okay. Two ounces per chicken piece. Use the back of a spoon or your fingers (I’ve done both), and spread it on top.

Step 5: Wilt that spinach.
Throw it in a skillet for a few minutes with a little oil or butter. You want it just soft, not mushy. Layer it on top of the cream cheese.

Step 6: Mozzarella magic.
Sprinkle the shredded mozzarella over each piece. Be generous. Cheese isn’t a place to cut corners.

Step 7: Bake.
Pop it in the oven. Twenty to thirty minutes later, you’ve got bubbling, browned cheesy goodness and perfectly cooked chicken underneath. Trust your nose—it’ll tell you when it’s done.

Want To Save This Recipe?

Enter your email below and we'll send the recipe straight to your inbox.

Storage Options:

Let it cool completely, then toss it in an airtight container. It’ll keep in the fridge for up to 3 days. Reheat in the oven if you want that cheese to crisp again, or microwave it for the lazy-but-still-delicious version.

Freezer? Yep, you can freeze it. But just know the texture might shift a little when you thaw and reheat. Still tastes good, just a bit less creamy.

Variations and Substitutions:

Thighs instead of breasts? Yes, absolutely. They stay super juicy.
Swap the cheese? Try provolone or gouda for a smoky vibe.
Add mushrooms or sun-dried tomatoes? I’ve done both, and honestly… chef’s kiss.
No Italian seasoning? Use oregano and basil. Or just salt and pepper if that’s all you’ve got.
Low-fat cream cheese? It works. Not quite as lush, but still satisfying.

What to Serve with Chicken Casserole with Spinach?

You don’t need much on the side, but if you’re feeling fancy (or hungry):

Garlic bread – To soak up the melty cheesy bits. Always a yes.
Roasted veggies – Brussels sprouts, carrots, zucchini. Whatever’s in season.
Mashed potatoes – For the cozy crowd.
Simple salad – Something crisp and citrusy to lighten things up.

Frequently Asked Questions:

Can I make this ahead of time?
Yep. Assemble it, cover, and refrigerate for a day. Just bake it fresh when you’re ready. Might need an extra 5–10 minutes in the oven if it’s cold.

Is it low carb or keto?
For sure. No pasta, no breadcrumbs. Just protein, cheese, and veggies.

Can I double the recipe?
Yes! You’ll need a bigger dish (or two). The more the merrier, especially if you’re feeding a crowd or meal prepping.

This Chicken Casserole with Spinach has saved my dinner plans more times than I can count. It’s easy, comforting, and just a little indulgent. And the best part? You can totally make it your own.

So go ahead—give it a try. Change it up. Make it messy. Make it yours. And when you do? Come back and tell me how it went. I’m all ears.

Real food, from one imperfect kitchen to another.

Remember it later!

Planning to try this recipe soon? Pin it for a quick find later!

Remember it later!

Planning to try this recipe soon? Pin it for a quick find later!

Keep the Flavor Coming – Try These:

Delicious Brown Sugar Glazed Ham Recipe

Homemade Cinnamon Rolls Recipe

How To Cook A Perfect Ribeye Steak Recipe