To make these Pumpkin Cookies with Cream Cheese Frosting gluten-free, substitute the all-purpose flour with a high-quality 1:1 gluten-free flour blend that includes xanthan gum or a similar binding agent. Ensure all other ingredients, such as baking powder and powdered sugar, are certified gluten-free to avoid cross-contamination. The texture may vary slightly, but the cookies will remain soft and flavorful.