This Homemade Tapioca Pudding is naturally free of gluten. Tapioca, which comes from the cassava root is an alternative to thickeners made from flour for those who avoid gluten. However it's crucial to ensure that every ingredient used, including vanilla extract and store-bought milk is certified gluten-free. During processing there can sometimes be a risk of cross contamination. Therefore it's always important to check the labels to ensure that your delicious bowl of tapioca pudding not only tastes amazing but also meets all your gluten-free requirements and is completely safe, for you.