Turning this beloved recipe into a gluten-free delight is absolutely possible! To make these Easy Nebraska Runzas gluten-free, swap out the traditional wheat-based rolls with gluten-free roll dough available at many grocery stores or prepare your own gluten-free dough. Ensure the flour used for dusting and thickening is also gluten-free. By making these thoughtful substitutions, you can savor all the comforting flavors of the Midwest while accommodating gluten-free dietary preferences.