If you’re looking to make this dish gluten-free, it’s actually pretty easy! Just swap out the panko breadcrumbs for gluten-free breadcrumbs and use your favorite gluten-free pasta in place of the shells. For the sauce, double-check that your Worcestershire sauce and beef broth are gluten-free, as these can sometimes have hidden gluten ingredients. With these small changes, you’ll still get that creamy, comforting pasta bake experience—minus the gluten!