To make this Classic Bisquick Cheeseburger Pie gluten-free. Simply substitute the regular Bisquick. With a gluten-free version. Most grocery stores carry a gluten-free Bisquick mix. That works just as well. Be sure to check that your Worcestershire sauce is also gluten-free. As some brands contain gluten. With these simple swaps. You can enjoy. All the comforting flavors of this cheeseburger pie. Without the gluten. Making it a great option. For those with dietary restrictions.