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+ servings
Close-up of a comforting chicken casserole topped with fluffy biscuits.

Chicken and Biscuits Casserole Recipe

Prep Time 10 minutes
Cook Time 40 minutes
A comforting Chicken and Biscuits Casserole Recipe featuring tender chicken, vegetables, cheddar cheese, and golden biscuits baked in a creamy sauce.
6 Servings

Ingredients

  • 2 cans 10.5 oz each condensed cream of chicken soup, undiluted
  • 1 cup milk
  • 1 teaspoon garlic powder
  • 1 teaspoon poultry seasoning
  • 1/2 teaspoon black pepper
  • 1 can 12 oz refrigerated biscuits
  • 1 cup frozen peas and carrots
  • 1 cup cheddar cheese grated
  • 3 cups cooked chicken shredded or chopped
  • Kosher salt to taste

Instructions
 

Prepare the oven and dish

  1. Preheat the oven to 375°F (190°C). Lightly grease a 9x13-inch baking dish with nonstick cooking spray to prevent sticking.

Combine the base mixture

  1. In a large mixing bowl, whisk together the condensed cream of chicken soup, milk, garlic powder, poultry seasoning, and black pepper until smooth and well blended.

Incorporate the biscuits

  1. Separate the refrigerated biscuits and cut each into four equal pieces. Add the biscuit pieces to the soup mixture and stir carefully to coat them evenly.

Add remaining ingredients

  1. Stir in the frozen peas and carrots, cooked chicken, and grated cheddar cheese. Mix until all ingredients are well distributed.

Transfer to the baking dish

  1. Pour the combined mixture into the prepared baking dish, spreading it evenly to ensure consistent baking.

Bake the casserole

  1. Place the dish in the oven and bake for 35 to 45 minutes, or until the biscuits are puffed and golden brown and the filling is bubbling.

Rest before serving

  1. Allow the casserole to cool for at least 5 minutes before serving to let the filling set and to avoid burns.

Notes

To make this Chicken and Biscuits Casserole Recipe gluten-free:
  • Use a certified gluten-free cream of chicken soup.
  • Replace the refrigerated biscuits with a gluten-free biscuit mix or pre-made gluten-free biscuits.
  • Confirm that all additional ingredients, including seasonings and cheese, are labeled gluten-free.
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