To make this Chicken Alfredo Recipe gluten-free. Simply replace the rotini pasta. With your favorite gluten-free pasta. Ensure that your bacon. And cream of chicken soup are gluten-free. Or make a homemade gluten-free cream of chicken soup. For the Alfredo sauce. Use a gluten-free flour blend. Instead of regular flour. With these easy substitutions. You can enjoy all the creamy, cheesy goodness of this dish. Without any gluten concerns. Your family won't even notice the difference!