This recipe can be made gluten-free with minimal adjustments. The majority of the ingredients are naturally gluten-free; however, it is essential to use a certified gluten-free vanilla instant pudding mix, as some brands may contain additives derived from gluten sources. Verify that all packaged ingredients, including marshmallow creme and chocolate chips, are labeled gluten-free to ensure complete safety for individuals with gluten sensitivities or celiac disease.