To prepare this dish gluten-free, substitute the saltine crackers with a certified gluten-free alternative (such as GF crackers or gluten-free oats). Replace the all-purpose flour used for dredging with a gluten-free flour blend or cornstarch. Ensure the cream of mushroom soup is labeled gluten-free, as many conventional varieties contain wheat-based thickeners. Always double-check ingredient labels to verify compliance.